本翻譯僅作學術交流用，無商業意圖，請勿轉載，如有疑議問請來信

近期研究顯示，使用遠紅外線對臥床型2糖尿病患者的下肢進行15分鐘的超熱治療，能在兩週內顯著降低氧化壓力指標8-epi-PGF2alpha。雖然血糖和HbA1c水平未見變化，但TNFalpha水平上升，顯示超熱治療可能有益於緩解氧化壓力，為臥床患者帶來新希望。

使用遠紅外線對臥床型2糖尿病患者下肢進行超熱的效果

The effect of leg hyperthermia using far infrared rays in bedridden subjects with type 2 diabetes mellitus

Akihiko Kawaura 1, Noritoshi Tanida, Masato Kamitani, Junichi Akiyama, Masatoshi Mizutani, Naoko Tsugawa, Toshio Okano, Eiji Takeda
Affiliations expand
PMID: 20424670 DOI: 10.18926/AMO/32849

https://pubmed.ncbi.nlm.nih.gov/20424670/

我們研究了對使用遠紅外線的臥床型2糖尿病患者下肢進行超熱15分鐘治療的兩週效果對氧化壓力的影響。研究招募了四名由於中風而致殘的受試者（男1名，女3名）。所有病人都被收治於高橋中央醫院，並食用相同的醫院餐點。在住院、局部加熱腿部之前和之後的2週，測量了空腹血糖、HbA1c、腫瘤壞死因子(TNF)alpha、游離脂肪酸、瘦素、脂聯素和氧化壓力的標記——8-epi前列腺素F2alpha(8-epi-PGF2alpha)的血漿水平。結果顯示，血漿中的8-epi-PGF2alpha總量顯著下降，而TNFalpha水平顯著上升。另一方面，研究期間，葡萄糖、HbA1c、游離脂肪酸、瘦素和脂聯素的水平沒有變化。這些結果表明，重複的腿部超熱治療可能有助於保護免受氧化壓力的影響。

We examined the effect of leg hyperthermia on oxidative stress in bedridden subjects with type 2 diabetes mellitus using 15-min sessions of far infrared rays over a two-week period. Four subjects (male 1, female 3) incapacitated by a stroke were recruited for this study. All patients were admitted to Takahashi Central Hospital and ate the same hospital meals. Fasting plasma glucose, HbA1c, tumor necrosis factor (TNF)alpha, free fatty acid, leptin, adiponectin and plasma 8-epi-prostaglandin F2alpha (8-epi-PGF2alpha) levels as a marker of oxidative stress were measured on admission, just before and 2 weeks after local heating of the leg. Results showed that plasma total 8-epi-PGF2alpha levels were decreased significantly while TNFalpha levels were increased significantly. On the other hand, glucose, HbA1c, free fatty acid, leptin and adiponectin levels were not changed during the study period. These results suggest that repeated leg hyperthermia may protect against oxidative stress.