新研究:指尖血與全血三酸甘油脂測量具高度相關性

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在一項涵蓋50名無心血管疾病受試者的研究中,比較了指尖血與全血的三酸甘油脂(TG)測量。研究發現,儘管指尖血的TG水平普遍較高,兩種方法之間存在著極高的相關性(相關係數為0.95)。此外,研究提出了從指尖血TG估算全血TG的回歸方程式,並發現男女之間有顯著差異。

Measurement of triglycerides in capillary blood: validation against whole blood measurement

測量毛細血管血液中的三酸甘油酯:相對於全血測量的驗證

Alegría Barrero A, Cordero Fort A, Moreno Arribas J, Rodríguez Manero M, Alegría Ezquerra E. Concordancia entre la determinación de triglicéridos en sangre capilar y por el método tradicional [Measurement of triglycerides in capillary blood: validation against whole blood measurement]. Med Clin (Barc). 2009;133(10):375-378. doi:10.1016/j.medcli.2008.12.023

https://pubmed.ncbi.nlm.nih.gov/19359013/

Abstract

Background and objective

Elevated plasma triglycerides (TG) are an independent cardiovascular risk factor and a part of metabolic and postprandial syndromes. Capillary analysis of TG would facilitate the recognition of those abnormalities. The aim of the present study was to assess the concordance between TG values measured in capillary (Accutrend GCT Roche Diagnostics) and total blood.

Patients and methods

Total blood and capillary TG were analyzed in 50 subjects without cardiovascular disease.

Results

Mean capillary TG were higher than total blood TG (116.5mg/dl vs 86.0mg/dl; P<.001); a good correlation between both methods was obtained (r=0.95; P<.001).

Conclusions

in this cohort of consecutive unselected subjects we found that capillary TG measurement correlates well with total blood analysis and that there are significant differences between men and women. We propose regression equations to estimate blood TG from capillary measurements: men: capillary TG X 0,837; women: capillary TG X 0,698.

摘要

背景與目的

血漿三酸甘油酯(TG)升高是獨立的心血管危險因素,也是代謝綜合症和餐後綜合症的一部分。毛細血管分析TG有助於識別這些異常。本研究旨在評估毛細血管(Accutrend GCT Roche Diagnostics)和全血測量的TG值的一致性。

患者與方法

對50名無心血管疾病的受試者進行全血和毛細血管TG分析。

結果

毛細血管TG的平均值高於全血TG(116.5mg/dl對86.0mg/dl;P<.001);兩種方法之間取得良好的相關性(r=0.95;P<.001)。

結論

在這組連續未選擇的受試者中,我們發現毛細血管TG測量與全血分析有良好的相關性,且男女之間存在顯著差異。我們提出迴歸方程式以從毛細血管測量估算全血TG:男性:毛細血管TG X 0.837;女性:毛細血管TG X 0.698。