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研究展示了一種創新的生物標誌物檢測技術,能在短時間內分析單滴血液,有效協助早期診斷代謝性疾病。這項技術結合微流體裝置、迷你生物感測器和數據轉換器,可快速生成患者獨特的生物資料檔案,促進更個體化和有效的治療方案。此外,智慧型手機應用程式的自我監測功能將進一步提升治療成效。
臨床檢測與Point-of-Care治療於代謝性疾病
Point-of-Care Testing and Personalized Medicine for Metabolic Disorders
Guest FL, Guest PC. Point-of-Care Testing and Personalized Medicine for Metabolic Disorders. Methods Mol Biol. 2018;1735:105-114. doi:10.1007/978-1-4939-7614-0_6
https://pubmed.ncbi.nlm.nih.gov/29380309/
摘要
本章描述了生物標誌物檢測的創新,這些檢測可以促使患有代謝性疾病的患者得到更早及更好的治療。使用新的微流體裝置,配合迷你化的生物感測器和轉換器,能在一次典型的醫生診所訪問時間內分析一滴血的資料。這些方法正在進行中,將結合生化和臨床數據,為每位患者產生獨特的生物資料檔案。這將允許更早、更個體化和更有效的治療選擇。此外,用於自我監測的智慧型手機應用程式將日益被使用,以達到最佳的患者治療效果。
Abstract
This chapter describes innovations in biomarker testing that can facilitate earlier and better treatment of patients who suffer from metabolic disorders. The use of new microfluidic devices along with miniaturized biosensors and transducers enables analysis of a single drop of a blood within the time frame of a typical visit to a doctor’s office. Steps are underway so that these approaches will incorporate both biochemical and clinical data, resulting in unique bioprofiles for each patient. This will allow earlier, personalized, and more effective therapeutic options. In addition, smartphone apps for self-monitoring will be used increasingly for the best possible patient outcomes.